This paper presents the preliminary results of an analytical study on domestic pottery samples originating from the Copper Age sites of Casetta Mistici, Tor Pagnotta, Osteria del Curato-Via Cinquefrondi, Torre della Chiesaccia and Valle dei Morti, all of which are located in the Rome area (Latium, Italy). The aim of this research is to define the compositional features of the ceramic pastes and to reconstruct the main technological choices characterising pottery production in these contexts. The importance of these archaeological sites lies in their geographic position, being located in an area bounded by the Tiber and Aniene rivers and the Colli Albani volcano, and in their stratigraphic sequence, spanning from the mid-fourth to the end of the third millennium bc. This research, based on a petrographic and chemical investigation of pottery samples, led to the distinction of eight petrographic groups that reflect specific choices in pottery production. Moreover, the analytical results provide indications about the prehistoric pottery production of the Rome area in relation to the ceramic recipes used, the pastes that were obtained and their sourcing areas.